Exploration of Temporal Resolution in Mouse Primary Visual Cortex (V1)

Abstract

When thinking about regions of the brain responsible for timing activity, one may first think of high order cortical areas like the medial prefrontal cortex, supplementary motor area, or even the suprachiasmatic nucleus in the hypothalamus.(1) However, recent studies have found compelling evidence that even the lowest order region of the brain’s visual system, the primary visual cortex (V1) is implicated in timing.(2) Building on previous research from the Berry Lab at Princeton University, this paper offers a deeper dive into what kind of timing-related visual responses arise in the primary visual cortex of a mouse brain, and offers some possible mechanisms for such activity.