Please use this identifier to cite or link to this item: http://arks.princeton.edu/ark:/88435/dsp01gf06g581b
DC FieldValueLanguage
dc.contributor.authorMiller, Ian
dc.contributor.otherEcology and Evolutionary Biology Department
dc.date.accessioned2022-06-13T17:49:28Z-
dc.date.available2022-06-13T17:49:28Z-
dc.date.created2022-01-01
dc.date.issued2022
dc.identifier.urihttp://arks.princeton.edu/ark:/88435/dsp01gf06g581b-
dc.description.abstractInfectious diseases are an integral part of natural ecosystems but also pose a serious threat to human health and agriculture. Understanding the multitude of factors shaping the epidemiology and evolution of pathogens is crucial for predicting and mitigating their effects, especially in a rapidly changing world. In this dissertation, I present four studies about how vaccination, emerging pathogens, and climate change affect the epidemiology and evolution of infectious disease. In the first chapter I consider the effects of toxin targeting vaccines, such as acellular pertussis vaccines, on the evolution of pathogen virulence. In the second chapter I map projections of the expected burden of the novel coronavirus SARS-CoV-2. In the third chapter I assess the risk for COVID-19 vaccines to drive the evolution of increased viral virulence. In the fourth chapter I investigate how climate change will alter the epidemiology of fungal plant pathogens using the flax rust system as a model.
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.publisherPrinceton, NJ : Princeton University
dc.relation.isformatofThe Mudd Manuscript Library retains one bound copy of each dissertation. Search for these copies in the library's main catalog: <a href=http://catalog.princeton.edu>catalog.princeton.edu</a>
dc.subjectCOVID
dc.subjectdisease ecoology
dc.subjectflax rust
dc.subjectpathogen
dc.subjectvirulence
dc.subject.classificationEcology
dc.subject.classificationEpidemiology
dc.subject.classificationEvolution & development
dc.titleTHE ECOLOGY AND EVOLUTION OF PATHOGENS IN A CHANGING WORLD