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Title: Fatty Acid Metabolism in Plasmodium falciparum:Elongation and Desaturation in Minimal Media
Authors: Pak, Grace
Advisors: Llinas, Manuel
Department: Chemistry
Class Year: 2013
Abstract: Plasmodium falciparum, the deadliest of the malaria parasites, rapidly grows and divides in the human blood stage of its life cycle. It has a high demand for lipid production. Instead of biosynthesis, however, it is thought that P. falciparum has the ability to modify fatty acids through elongation or desaturation. This biochemistry is best visualized if metabolic labels are not diluted. Utilization of minimal media and LC/MS confirms with high resolution the parasite's ability to elongate fatty acids.
Extent: 46 pages
Access Restrictions: Walk-in Access. This thesis can only be viewed on computer terminals at the Mudd Manuscript Library.
Type of Material: Princeton University Senior Theses
Language: en_US
Appears in Collections:Chemistry, 1926-2017

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