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Please use this identifier to cite or link to this item: http://arks.princeton.edu/ark:/88435/dsp012z10ws57q
Title: Progress Towards the Total Synthesis of Pisiferol
Authors: Wilson, Jessica Laura
Advisors: Sorensen, Erik J.
Department: Chemistry
Class Year: 2015
Abstract: Pisiferol is an abietane diterpene with antitumor, antifungal and antibiotic activities. It features a complex tricyclic core structure with a trans-ring junction and an axial methanolic group. I discuss different approaches to render the synthesis asymmetric within the context of previous work done by the Sorensen laboratory. Because the key steps in the synthesis pathway have already been validated using racemic material, if successful, these efforts would render the asymmetric total synthesis of pisiferol complete.
Extent: 101 pages
URI: http://arks.princeton.edu/ark:/88435/dsp012z10ws57q
Type of Material: Princeton University Senior Theses
Language: en_US
Appears in Collections:Chemistry, 1926-2016

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